The article "AIDS: 30 Years of progress and promise assisted by La Jolla researchers"  includes references to several La Jolla-based UCSD HIV/AIDS researchers and research programs, including Dr. Igor Grant and the Translational Methamphetamine AIDS Research center (TMARC), with general descriptions of the state of AIDS research 30 years into the epidemic.

To Cite:
Friedmann, L. (2011, Nov. 30). AIDS: 30 years of progress and promise assisted by La Jolla researchers. La Jolla Light.

Click Here to Read the Full Article.

Findings reported in the manuscript Human Immunodeficiency Virus Infection of Human Astrocytes Disrupts Blood-brain Barrier Integrity by a Gap Junction-dependent Mechanism published in the June 29^th Issue of the Journal of Neuroscience indicate that astrocytes may lead the way to understanding neurocognitive impairment in HIV infection.  Dr. Grant stated, “This study provides a possible explanation indicating that minute numbers of infected astrocytes can trigger a cascade of signals that could open the brain to various toxic influences."  Eliseo Eugenin, primary author of the study, constructed a blood-brain barrier model using human cells and found that infection of astrocytes may be important in promoting neurocognitive impairment that so commonly travels with HIV infection, possibly by weakening the blood-brain barrier allowing infection of brain cells.

For the article in HealthDay News click here.

For redirect to the abstract of the published manuscript and Journal Information click here.